• What is Bioidentical Hormone Replacement Therapy (TRT)?
• The Benefits of TRT
• The Risks and Side Effects of TRT
• How is TRT Administered?
• Who is a Good Candidate for TRT?

Hormone Replacement Therapy (TRT), often referred to as Bioidentical Hormone Replacement Therapy (BHRT) when specifically using hormones that are chemically identical to those naturally produced in the body, has become an increasingly popular treatment for men and women seeking to address hormone imbalances.

As we age, certain hormone levels naturally decline, leading to a variety of symptoms ranging from fatigue, decreased libido, and muscle loss to mood swings, anxiety, and cognitive decline. TRT aims to restore these hormone levels to a more youthful state, improving overall quality of life.

What is Bioidentical Hormone Replacement Therapy (TRT)?

Hormone Replacement Therapy (TRT) involves administering synthetic or bioidentical hormones to replace or supplement low hormone levels in the body. These hormones contribute to muscle mass, bone density, red blood cell production, mood regulation, and libido. As men age, their natural hormone production declines, typically starting around age 30, with levels continuing to decrease as they get older.

TRT aims to counteract these effects, helping to restore normal hormone levels in deficient individuals. This therapy can be delivered in several forms, including injections, topical gels, pellets, and patches, each with its advantages and considerations.

The Benefits of TRT

There are several potential benefits of TRT, particularly for individuals who have clinically low hormone levels. While every patient is different, many people report experiencing:

• Increased energy levels – A common symptom of low hormones is fatigue. Many TRT patients report feeling more energetic and alert after starting therapy.
• Improved mood and mental clarity – Hormones play a role in mental health, and replacing low levels may help alleviate symptoms of depression, irritability, and brain fog.
• Enhanced libido – One of the most noticeable effects of low hormones is a decrease in sexual desire. TRT can improve libido and sexual function in many individuals.
• Increased muscle mass and strength – Hormones are essential for muscle development, and TRT can help preserve or increase muscle mass, particularly in aging adults.
• Improved bone density – Low hormones can be associated with lower bone mineral density, which can increase the risk of fractures. TRT can help reduce this risk.
• Better sleep – Some individuals report that TRT improves sleep quality and reduces symptoms of insomnia.

The Risks and Side Effects of TRT

While TRT can be highly beneficial for individuals with clinically low hormones, it is not without its risks and potential side effects. Some common side effects include:

• Acne and oily skin – Increased hormones can lead to an overproduction of sebum, which may result in acne.
• Hair loss – TRT may accelerate hair loss, particularly in individuals predisposed to male pattern baldness.
• Mood swings or irritability – Some individuals may experience heightened aggression or mood swings when undergoing TRT.
• Sleep apnea – TRT has been associated with an increased risk of sleep apnea, especially in individuals who are already predisposed to the condition.
• Increased red blood cell count – Elevated hormones can lead to an increase in hematocrit levels, which may increase the risk of clotting and other cardiovascular issues.

Before starting TRT, individuals need to undergo a thorough evaluation, including blood tests and an assessment of their overall health, to determine if the therapy is appropriate and safe for them.

How is TRT Administered?

There are several methods for administering TRT, each with its own set of advantages and drawbacks. The most common options include:

• Injections – Administered either intramuscularly or subcutaneously, injections are typically given every 1-2 weeks. This method provides a consistent and high level of hormones but may require regular visits to a healthcare provider or self-injection at home.
• Topical Gels and Creams – Applied directly to the skin, these formulations allow bioidentical hormones to be absorbed transdermally. They provide a more consistent release of hormones throughout the day, but there are concerns about the potential for skin-to-skin transmission to others.
• Pellets – Small pellets are inserted under the skin, typically in the hip or buttocks. The pellets release a steady dose over 3-6 months. This method is convenient but requires a minor surgical procedure for insertion.
• Patches – These are worn on the skin, releasing a steady dose of hormones over 24 hours. However, they may cause skin irritation in some users.

The choice of treatment often depends on patient preferences, lifestyle, and the advice of a healthcare provider.

Who is a Good Candidate for Hormone Replacement Therapy (TRT)?

Not everyone is a suitable candidate for TRT. While TRT is primarily used to treat low hormone levels, individuals need to have a confirmed diagnosis of hypogonadism based on both symptoms and blood tests. Some potential candidates for TRT include:

• Men with clinically low hormone levels – Typically, a level below 300 ng/dL is considered low.
• Individuals with symptoms of low hormones – These may include fatigue, decreased libido, muscle weakness, depression, and cognitive decline.
• Patients with age-related hormone decline – While these hormones naturally decline with age, treatment is typically reserved for individuals with significant symptoms or below-normal levels.
• Those with specific medical conditions – Certain conditions, like obesity, diabetes, or hypopituitarism, can lead to low hormone levels and may benefit from TRT.

However, individuals with a history of prostate cancer, untreated sleep apnea, or certain cardiovascular conditions may not be appropriate candidates for therapy. A healthcare provider can help assess risk factors and determine if TRT is right for you.

Next Steps: MixMyRx Memberships

TRT can offer significant benefits for individuals struggling with the effects of low hormones, from increased energy and improved mood to better muscle mass and sexual function. Individuals should be evaluated by a healthcare professional to ensure that it is appropriate for their needs. This is where a personalized and convenient approach to treatment can make all the difference.

Our goal at MixMyRx is to make Hormone Replacement Therapy as convenient as possible. Membership offers many benefits, including:

• Save up to 60% on compounded medications
• Standardized pricing of either $19 or $29 (depending upon the medications)
• Easy access to counseling for your prescription
• Access to most common generic medications
• Access to a team of experienced clinical physicians, with many specializing in Hormone Replacement Therapy
• Fast, free, shipping that delivers your prescriptions directly to you in 48 states and Washington D.C.

Become a member of MixMyRx if you are experiencing any symptoms of hormone imbalance.